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Product Description
L243
IgG2a
FCM
CF-Blue
Please refer to the Certificate of Analysis for the lot-specific concentration.
Mononuclear cell leukemia acute undifferentiated
Human
The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
RUO
HLADR, clone L243, is a mAb intended for the identification of all human B cells, monocytes and activated T cells. This reagent is effective for direct IF staining of human tissue for FCManalysis using ≤1 μg/106 cells.
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This antibody reacts with the HLADR antigen, which is is present on dendritic cells, monocytes, macrophages, B cells, Haemopoietic precursor cells, activated T and NK cells, as well as some epithelial cells. The mouse monoclonal antibody L243 recognizes specifically HLA-DR molecules, both peptide-loaded and empty. It does not cross react with HLA-DP and HLA-DQ. Clone L243 binds a conformational epitope on HLA-DR? which depends on the correct folding of the ?? heterodimer.