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ERK1/2 (pT202/Y204) Antibody
品牌:Abbexa
貨號:abx011510
規格:100 μg
貨期:

ERK1/2 (pT202/Y204) Antibody

商品詳情 參考文獻 相關資料
Phospho-ERK1/2 (Thr202/Y204) Antibody detects endogenous levels of ERK1/2 only when phosphorylated at Threonine 202/Yosine 204. Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.

Target ERK1/2 (pT202/Y204)
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Tested Applications WB, IHC
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Immunogen A synthesized peptide derived from human ERK1/2 around the phosphorylation site of Threonine 202/Tyrosine 204.
Purification Immunogen affinity purified.
Conjugation Unconjugated
Storage Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Molecular Weight 42 kDa - 44 kDa
Swiss Prot P27361 P28482
Buffer Rabbit IgG in PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
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