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Biological Activity:

BAZ2-ICR is a potent and selective BAZ2 bromodomain inhibitor with Kd values of 109 and 170 nM for BAZ2A and BAZ2B, respectively. It exhibits 15-fold selectivity for the BAZ2 bromodomain over the CERC2 bromodomain and >100-fold selectivity over a range of other bromodomains. It shows accelerated FRAP recovery at 1 μM in the BAZ2A FRAP assay.

How to Use:

In vitro:? BAZ2-ICR was used at 1-10 μM final concentration in various in vitro assays.

In vivo: n/a

Reference:

• 1.????? http://www.thesgc.org/chemical-probe/BAZ2-ICR

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Products are for research use only. Not for human use.?