產品介紹 品名 C4 Monoclonal Antibody to Human C4 Binding Protein 貨號 A215 規格 100 μL 同種型 IgG2bK 蛋白質濃度 > 1.0 mg/mL 緩沖液 Borate Buffered Saline (pH 8.4 ± 0.2) 物種交叉反應 Human, baboon 儲存 ≤ 30 Days 2-8?C > 30 Days ≤ –20?C 使用說明 For Research Use Only. Not for use in diagnostic procedures 產品描述 A murine monoclonal antibody to an epitope on C4 Binding Protein. This monoclonal antibody was raised against purified human C4 Binding Protein. Quidel's C4 Binding Protein monoclonal antibody has been used in a variety of experimental techniques including EIA, Western Blot, and Immunohistochemistry. 特異性 The specificity of the monoclonal antibody was established via a series of immunoassays. First, the antibody was shown by ELISA to bind purified C4 Binding Protein (C4BP) immobilized in microtiter wells. Second, free (unbound) C4BP and human serum were shown via inhibition EIA to inhibit the binding of this antibody to immobilized C4BP. Other complement proteins, including C4, did not inhbit binding 應用 參考資料 1、Roos, A. et al. Glomerular activation of the lectin pathway of complement in IgA nephropathy is associated with more severe renal disease. J Am Soc Nephrol 17:1724-1734 (2006). 2、 Grosskinsky, S. et al. Human complement regulators C4b-Binding Protein and C1 Esterase Inhibitor interact with a novel outer surface protein of Borrelia recurrentis. PLOS Neglected Tropical Diseases 4(6):e698 (2010)
產品介紹
C4 Monoclonal Antibody to Human C4 Binding Protein
A215
100 μL
IgG2bK
> 1.0 mg/mL
Borate Buffered Saline (pH 8.4 ± 0.2)
Human, baboon
≤ 30 Days 2-8?C > 30 Days ≤ –20?C
For Research Use Only. Not for use in diagnostic procedures
A murine monoclonal antibody to an epitope on C4 Binding Protein.
This monoclonal antibody was raised against purified human C4 Binding Protein.
Quidel's C4 Binding Protein monoclonal antibody has been used in a variety of experimental techniques including EIA, Western Blot, and Immunohistochemistry.
The specificity of the monoclonal antibody was established via a series of immunoassays. First, the antibody was shown by ELISA to bind purified C4 Binding Protein (C4BP) immobilized in microtiter wells. Second, free (unbound) C4BP and human serum were shown via inhibition EIA to inhibit the binding of this antibody to immobilized C4BP. Other complement proteins, including C4, did not inhbit binding
1、Roos, A. et al. Glomerular activation of the lectin pathway of complement in IgA nephropathy is associated with more severe renal disease. J Am Soc Nephrol 17:1724-1734 (2006).
2、 Grosskinsky, S. et al. Human complement regulators C4b-Binding Protein and C1 Esterase Inhibitor interact with a novel outer surface protein of Borrelia recurrentis. PLOS Neglected Tropical Diseases 4(6):e698 (2010)
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